When I had a 75 I initially had a coral beauty. I then tried to add a flame, it didnt work. The CB tried to kill the flame and was truly relentless. Needless to say I removed the flame and added it to another aquarium. A week later I tried again, this time with a cherub angel. Apparently the CB did not view the cherub as a threat and has never bothered it. Today the CB, cherub, and a flame/rusty hybrid all live together inside a 120. Basically if you have extra tanks to put a fish in if it doesnt work I would try, if you only have one tank I would not try it.