Probably not IMHO. I think your tank may be big enough, but I think it's marginal in size for a sand cleaning cucumber. They can get quite big. I have a 180g and the entire bottom is sand (almost no rock sitting on the sand) and the 3" yellow cucumber I got 2 years ago is now about 12" long. And it does clean the sand of some organics, buy it's not going to make the sand 'white'.