It certainly merits further investigation, I think. The serpent star I mentioned had been with me for some time (~2 years) and had grown rather robust in his time in my tank. I noticed that he had begun to sit on the light-facing surface of the rocks at the back of the tank, even during daylight hours instead of stay safely secluded in darkness as had been his previous habit. A few days after he started doing that, I noticed small injuries appearing at the base of two of his arms, which gradually expanded as if he were disintegrating. Over the course of a week or so, despite attempts to isolate him within the tank, he deteriorated further and eventually died. I concluded he must have been harrassed to death by SOMETHING in the tank, but could not settle on a culprit.
When I caught the little amphipods apparently chewing on the delicate skin of my cucumber, I thought I'd solved the mystery. I'll have to find someone who can identify the specimens I captured to species.