Agreed, but locking the flange on with a non-permanent sealant such as silicone, helps prevent it from creeping loose over the years, similar to that lock-tite stuff you can put on nuts and bolts. Maybe this too is not that necessary, but I seem to have this creeping flange problem with bulkheads that feed large vibrating pumps.
Like I mentioned, I'd only use it as a leak-sealant crutch for this exact reason (too large of a hole), and only on very small tanks, and only on the threads, not the gaskets.