I have always run my tank (120g mixed reef) with no skimmer, no sump. The tank has a DSB with plenum, a little heavy on the live rock, and light on the fish. Water changes of 20 gal every two months. Tank has had no problems (knock on wood) for 2+ years, coral growth is great, and everything seems healthy. I do remove detritus build up every three months or so. Test it weekly to ensure parameters are correct - feeding the corals is as simple as stirring the substrate a little bit and getting some 'snow' in the water column.