General rule of thumb isn't much help on this. About like asking "as a general rule of thumb, how much wind will it take to blow down my 2 story house?" The answer would be it depends basically on how old the house is. If it's 100 years old and hasn't been maintained, it may not take much wind, but if it's a year old, it may withstand a lot of wind. It would also depend if it was well built or built by someone that didn't know what they were doing. The above answers were good once the age and location were determined. Even then that's not exact as there can be some variables.