rapid tissue necrosis (sp?) = basically the tissue sheds off of your acro usually within a day. Perfect water/light/food/conditions is the only way to prevent. Sinse we cannot achieve this, keeping everything as close to ideal parameters is your best preventative measure. Sorry for being so vague, it could be caused by any number of things and we could fill a board with all of the stuff that can kill an acro (actually just read this board, we already have). All of the things that people typically tell you not to do with acros could potentially cause rtn or any number of negative syndromes.
-John-