Won't know unless you try. One of the most exciting things, and frustrating at the same time, is that there are no absolutes in this hobby. It comes down to whether or not to gamble. I took the gamble. I put four angels (female watanabe, flame, coral beauty, and an atlantic pygmy) into my 300 gal. reef. It's been almost two years with only two casualties (spiny gorgonian and an open brain). I provide seaweed (green and purple), in addition to a varied frozen diet, daily. Other than the two casualties listed, I've observed very little nipping from my angels. Also, my maxima clam is doing fantastic. For me, it has been totally worth it! For you, would it be worth it? Good luck!!!