I've melted them with too much light, I has one melt mysteriously for 40+ polyps down to one. I managed to save it and it's back up to 8 polyps now. I recently had a mini tube worm\mini duster growing on the bottom of the frag, it seemed to make them mad and they were slowly melting away. I killed the worm\duster and they look healthier than they have in quite a while.
I've also done freshwater dips combined with quarantine to keep the pods from picking at the dying tissue. It seemed to slow the disappearance of polyps, and managed to save the one frag. Luck, most likely, but it seemed to work.
Scott