it will be a good idea to. they are known to cause high nitrate levels. anything with bio in its name will cause this. the reason is the bacteria that lives on the bio media will break down ammonia to nitrites, then nitrites to nitrates, but it cant break down the nitrates to nitrogen gas. therefore the nitrates cant exit the water. if you have a FO tank then the nitrates arent really a problem. with a reef though nitrate levels as low as 5 ppm can cause problems with corals and some inverts.