I have an established Brackish tank up and running right now and have had great success with it. My tank consisted of 1 green spotted puffer and 2 mollies. The puffer started out in water at around 1.006 or so and the mollies were full fresh. With the green spotted puffer they thrive best at full marine when they reach adulthood, the mollies however tend to do better ina full fresh or mildly brackish environment, not saying they won;t last in full marine, they just do better without it. I slowly bring my salinity up a little with each water change, and when I say a little i mean a little, the tank has been up and running for a little over a year now and it currently sits at 1.014, give or take .001. I still have the GSP and now have about 8-10 mollies including the original two, i haven't bought anymore, that was just from their hatchlings that survived. So some fish can be converted from fresh to full marine and some go through a gradual change as they get older. Many fish also tend to migrate from fresh to salt or salt to fresh to spawn. It can be done just do your research on what types of fish you are planning on getting.