Ventralis321
In Memoriam
I've had to treat for red bugs before and my tank is a 75 gal tank w/ 30 sump/refuge. I dosed about a 1/4 to a 1/3 and had no ill effects except some hermits dying and some crabs. My fish are never effected. Maybe it has to do with O2 levels when treating. I know that the skimmer has got to be turned off and that contributes to C02 building up. It's never been a problem for me but it may for other setups.