im doing the same tank and I say both.
Im doing an over the side closed loop, along with one or two 6100's and a wavebox.
Problems with closed loop is if you drill the tank it can leak and be a PINA, pipes are hard to hide and if done wrong they can suck more power then some powerheads for the same water movement.
power heads can also be hard to hide, and will have to be removed to be cleaned.
The answer. over the side closed loop. No leaks, no bulk heads and if anything goes wrong it can be turned off and disconnected. Flow wise ill be using eductors on the closed loop to increase the darts output 3-4x(10,800gpm min for 170 watts, not bad) If i need more ill upgrade to a super dart or baracuda. Pipes will be hidden behind the rockwork as I am making the rockwork around the piping system. It will also be on a timer to conserve power.
supplimnetal flow will be a tunze or two strapped to a seaswirl and a wave box, also with custom rock work to hide them.
and as for the "if it did fail" I can just remove the eductors and stick some power heads in the same holes in the rocks. But in all liklyhood if anything happened all I would have to do is clear a clogged eductor or replace the pump.