Good info in both responses. I attended a seminar awhile back and one of the subjects talked about (briefly) was the degradation of CDs and DVDs over time. I can't remember specific numbers, but tests have been done, and the time period for data loss was not very long at all. I was quite shocked. Hard drives, on the other hand, short of defects and externally induced file corruption issues are very survivable long term. Keep my pictures backed up on two hard drives (one internal and one portable) as well as an online backup system. As for the 1s and 0s themselves (i.e. the picture file), there's no danger there, except the loss of data Jacob & Cody talked about with compressed file formats like jpegs. But even with those, you can copy them to other locations as often as you want without a loss of data. It's just when you open up the file in an image editor and re-save it (whether you did any actual editing or not) that you may eventually see some degradation in the image itself.