Silicon will stick to acrylic - period.
Three months ago I built a wet dry/sump from a 30 gallon aquarium and used silicon to put acrylic baffels in place - I could pick the aquarium up by the baffels (which is what I did to carry it in the house). Alas, the tank broke (the bio tower put too much stress on the thin glass), so I built a custom wet dry/sump from acrylic last weekend.
I also, just last night, installed two acrylic overflows in my glass tank (Durso overflows, they are niiice). I was a bit worried with all the "silicon won't stick" mumbo jumbo, but I used it anyway. This morning I was pushing and pulling on the overflows to see if they would budge - nothing.
I've also called a plastic dealer, and they said silicon to glass/acrylic would be plenty strong for what I was trying to do with it. They went a step further and said that if I wanted any silicon aquarium to retain water over a long period of time I needed to silicon the seems - I don't really buy this one.
Now, I wouldn't build an aqurium with acrylic/silicon - but it will stick. It's not as strong of a bond as glass, but it'll do what you need it to do regarding overflows. I think this "silicon won't stick" crap is just crap, even aquarium manafacturers use silicon to install thier overflows from the factory.