Tim,
I have been using the Pro Brio S, and never refrigerated it, I am now, lol... So, I would say that might not work to automate. As far as Pro Bio F, I have been using the powdered form, I have been using this since the beginning. I simply mix it with tank water and pour that into the sump where I have matrix and siporax. I decided that more than likely it's use would better the diversity of bacterial strains, for this I went with both. FWIW, I did and do not use Bio S, as it is designed for setup bac population. This was unnecessary in my case.
