I don't have a breeding room but I do have a breeding tank that is working out really good on the small scale.
I have a 40b on with a 20 long sump. The 40b has 4 dividers giving it 5 equally divided spaces. The 20 long is divided in 3 sections. the first section has a drip tray with a spung filter and under that its filled with tufa rock (maybe 40 lbs) for bio filtration. The second section is just big enough for a protein skimmer, and finally the third compartment is for the return pump (I would advise making this section as big as possible so that you do not have to put water in every day, if its small it will go down really fast).
The 40b is plumbed to the 20 long using the glass holes over flow box.
When I set this tank up I was told you will never have the volume needed to keep the water perams high, and the fish happy. I was also told chances of getting them to breed would be vary slim. Well as of today I can prove them all wrong. I have three breeding pairs of clowns and I had a breeding pair of cardinals (they are in my display tank now). I feed these guys every time I think about them (sometimes 0 sometimes 5 times a day). I use a turkey baster about once every 3 or 4 weeks to clean the bottom. Doing that normally requires about 1 gallon of water. I also remove about 1 gallon of water every time I remove a clay pot. So total I may pull out about 1.5 gallons a week for water changes.
So as you can tell its not a big set up and its not too expensive. I am also not what you would call the most dedicated person to the aquarium. I pretty much leave it alone and the fish do their thing.