I did quite a bit of research on it before i decided to go that route. It is similar to dosing Vodka(didn't work good for me!), prodibio, zeo, ect...
One thing w/ adding the zeo supplements is that you need to add it slowly and your alk needs to be around 8. there is a zeo forum at zeovit.com that has a ton of info. for my 400 gallon system i add
0.9 mL of Start2 twice a day
2x per week i add
15ml coralsnow and 15 drops Zeo Bak
This did have a tremendous effect on my tank but every tank is different. This just helps feed the bacteria so it is grows larger and is big enough to be skimmed out of the tank...
Like I said there are many different ways to do this and you need ot be sure of what you are putting into yoru tank so you do not do more harm than good!