I'm doing it with a 120g in the house and about another ~140g in the garage. I am using a 1/2 hp chiller and it works very efficiently (was working reasonably well with a 1/3, but I got a good deal on the 1/2...it was working my old 1/4 WAY too hard, just for reference). I am using (2)x200w heaters, though I have another 200w heater in case it gets really cold. Everything runs through a little Reefkeeper Lite unit. My plumbing only has to run about 5 feet (dining room shares a wall with part of the garage wall), so I didn't need a pressure rated pump. I am using a Reeflo Dart; you will probably need something that can handle a little more pressure. Hope that helps.
-Ed