You won't really be able to feed them off the drain, but you can run them off the return. Though, for simplicity I usually keep the return and it's plumbing by itself and run reactors off separate, smaller pumps in the sump.
The drain would make it very difficult to control flow and might also affect water levels in the sump. Use a 1200 or other pump in the sump to drive media reactors. I have an oversized jaebo in my sump and I T off of that to drive my reactors, but I have tons of return flow.
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