I go away on weekends and long weekends with no problem.
I top up the sump a little higher before I go, and double the dose of Formula added, and when I come back, I top up and add whatever dosing still needed to be added.
I have ten systems on the go, and it's not tedious for me.
Asking for others opinions without experiencing it yourself may be doing yourself a disservice as it depends on your own feelings of what you want to put into the hobby, not what others have elected to do.
In some ways, the time it takes to service the tanks can be construed as a form of preventive maintenance as I look at the tanks closer when I'm doing any maintenance. If something doesn't look right, I can act on it then.