Yup I got spit at in the eye once with mushrooms. Took me out for about 30 minutes and about a day to clear up the reddness. Ever since I saw those threads about the potency of the toxins zoa's posses, I've been much more appreciative and glove wearing while handling them.
I've seen what looks more like a red stringy slime that emanates from things like mushrooms and other softies when disturbed as in fragging, but honestly I've never fragged intentially any zoa's to see this stuff.
By the way, the toxin can be so bad that even a small amount could cause bad things in a tank. I would recommend fragging with water-changed water or in some other water outside of the tank.