Yes
Yes
I never write brief and I hardly double space, sorry.
I am 1000% positive it works because I've been doing it for 9 years now. My current pico just hit 2.5 years on this approach, it's purple to the core and packed with corals as much per square inch as any large reef tank. The changes help, not hurt, and are a requirement for the way I pack corals into picos. I just match all the params and dump in the water, corals are opened up happy in 15 minutes every time. They get used to it quick. Most all the bazillion threads I've ever written about picos eventually wind up with this water change theory/practice, and I would also point back to work done on this site in the magazine I believe sometime in '04 that showed 20-30% changes don't do anything but accumulate wastes, which there is no room for in a pico. Larger tanks, and skimmed tanks, are more forgiving that's why so many get away with low level changes. My observations are anecdotal and centered around my low NO3 levels, I experimented with the change frequency to keep me under 15ppm and that amounted to bi-weekly 100%'s...but in this study they showed larger changes are needed, in the order of 50% iirc. I don't have to do it weekly, but I have had picos that did need it. my 1.5 gallon reefbowl gets this bi-monthly. The .5's got it weekly, when there was so much coral every square inch was comprised of living matter (that requires feed) along with shrimps and stars...
100% changes have nothing to do with poor design or quality approaches, they are designed to allow you to feed your system well instead of starving it and making corals live on their own energy stores as photosynthesis keeps them steady state for a while. By feeding well we can deliver the aminos, vitamins, proteins etc, so a pico reef can actually live longer than 3 months and be *growing* not just sitting there in near-starvation mode. Without feeding, the system gets stressed over time and will not thrive long term, although this cuts down on change needs. a non-fed system will not last years, period. Years should be the goal of any tank, and it's only my opinion the tank will go eutrophic in ~6 months if you don't change water aggressively. I guess it's possible to not do that and feed very lightly to prevent OTS in picos, but I'm not seeing any packed-tight picos living very long with the caloric-restriction or lax change approach.
I am absolutely certain it does not affect biofiltering, you have to give those little guys more credit than that!! I'm not being argumentative I'm just singing the praises of how this approach lets you pack corals into your tank in a ridiculous manner. Considering in a sporulated state 'somonads and 'bacters can live in your eyebrows, an oily puddle in the road or inside your microwave while it's being used, a few aggressive water changes simply do not affect these little ubiquitous wonders. They are bullet proof practically unless you zap em with antib's.
We wouldn't have algae problems in larger systems if changes were this aggressive, and it'd let you get away with a whole lot more feed which better represents nature anyway. Obviously it's not practical in large tanks, but in nanos, go for it and feed better than you currently do.