I recently dosed with NLS Ick Shield. It did the job, the ich is absolutely gone. I removed all reef critters except hermits and did a 4 week treatment. I've removed it with a water change, carbon and purigen. Put all my reef critters back and they're all fine. But then I had a massive GHA explosion (which I have NEVER had before) and my rocks give off this slime/mucous at night.
All in all, I would repeat this if necessary because it is better than the alternative, but be aware you may have some algae problems when the CP is removed. It is as if it put the algae on pause and the second the CP is gone the algae growth fast forwards 4 weeks. Im wondering if this is a result of removing it abruptly rather than over time.