Steven: Thank you for writing this article and bringing attention to the problem of cyanide use in the capture of marine fish. I would like to offer several observations from a medical perspective.
1. Treatment: To treat humans exposed to cyanide we generally use sodium nitrite and sodium thiosulfate. I guessing that sodium nitrite is not a good candidate because we all know about N02 toxicity in marine fish. Sodium Thiosulfate may be a better prospect, as I believe that people already use sodium thiosulfate to detoxify chlorine. One uncertainty in all this is that in medicine, we dose these medications intravenously. I have no idea if the medication would be absorbed directly from the water. Methylene blue may also be a possibility, but it may have more of a theoretical risk of overdose. Again, methylene blue is dosed IV in humans, so I donââ"šÂ¬Ã¢"žÂ¢t know to what degree it may be absorbed. Iââ"šÂ¬Ã¢"žÂ¢m not sure if we need to detoxify cyanide because Iââ"šÂ¬Ã¢"žÂ¢m not sure how long cyanide remains in the fishes tissue. If all or most of the cyanide has been metabolized or removed by the time it the fish reaches the consumer, there may be no indication for any further detoxification.
It would be very helpful to find out exactly how long it takes for the fish to clear all the cyanide from its body. If the cyanide is rapidly cleared, that is likely good for the fish. On the other hand, if cyanide is still present in the fishââ"šÂ¬Ã¢"žÂ¢s tissue at the time that it is received by the consumer, then there may be an opportunity to test the fish for cyanide. I have read that there is some testing of fish at the country of origin, but I believe that they test an actual tissue sample. I have been wondering if it is useful to test the water that the fish is shipped in. I know that there are simple and cheap test strips for testing for the level of cyanide in ground water. It would be a great tool for concerned LFS staff to able to test the shipping water for cyanide and then be able to avoid suppliers that are shipping out ââ"šÂ¬Ã…"œjuicedââ"šÂ¬Ã‚ fish. If we can test and know if the fish was exposed to cyanide, then by avoiding those suppliers, we could apply real economic pressure to discourage the further use of cyanide. If they canââ"šÂ¬Ã¢"žÂ¢t sell the fish, they will stop using cyanide.
2. Long term effects: I have no data at present to support this but my intuitive sense as physician tells me that there are likely negative long term effects. To understand the long-term effects one must understand a bit about how cyanide exerts its toxic effects on cells. Cyanide blocks the major pathway that cells use to generate energy. This results in cell death. It also results in a systemic acidosis within the fishââ"šÂ¬Ã¢"žÂ¢s tissues. Higher metabolism tissues are most susceptible to damage from this sort of metabolic insult. In humans we usually find that the nervous, cardiac, renal, and gastrointestinal organs suffer the greatest. Some fish receive a lethal dose and die right on the reef, but the fish that survive the initial insult very likely have some degree of vital organ damage. Now take this weakened animal and put through the rigors of shipping and transport it is no wonder that we see such high mortality.
Eric