Not sure if this has ever been attempted by anyone, but it would seem its a good marker for finding out if a fish is immune or not. From another forum,
Antibodies are proteins produced by the B cells of the immune system which bind specifically to antigens (an antigen is a molecule usually found on a pathogen's surface). They damage the pathogen either directly by inhibiting its function or secondarily by activating another series of proteins called the compliment cascade. Fish, although they only have one class of antibody, IgM, have very good antibody responses which can provide life-long protection against disease. This is why most farmed fish and some commercially-bred reef fish are vaccinated against common pathogens. After exposure to the pathogen or vaccine, full immunity takes about 6 weeks to develop so, provided the fish can be kept alive during this critical period of infection, there is a good chance that the anybodies, which circulate in the blood or mucus, will neutralise any further encounters with that pathogen.
I believe this would explain the vast majority of cases where there is ich/velvet present, but yet some die and other survive. Furthermore, I've found there is a way to test for immunity although its too rich for my blood to try.
https://www.mybiosource.com/prods/E...lobulin-M/IgM/datasheet.php?products_id=42385
Might be a possible good way for QT procedure, Find out if they have immunity and treat accordingly. In the presence immunoglobulin M (IgM), one may be able to assume there is a built up immunity.
Antibodies are proteins produced by the B cells of the immune system which bind specifically to antigens (an antigen is a molecule usually found on a pathogen's surface). They damage the pathogen either directly by inhibiting its function or secondarily by activating another series of proteins called the compliment cascade. Fish, although they only have one class of antibody, IgM, have very good antibody responses which can provide life-long protection against disease. This is why most farmed fish and some commercially-bred reef fish are vaccinated against common pathogens. After exposure to the pathogen or vaccine, full immunity takes about 6 weeks to develop so, provided the fish can be kept alive during this critical period of infection, there is a good chance that the anybodies, which circulate in the blood or mucus, will neutralise any further encounters with that pathogen.
I believe this would explain the vast majority of cases where there is ich/velvet present, but yet some die and other survive. Furthermore, I've found there is a way to test for immunity although its too rich for my blood to try.
https://www.mybiosource.com/prods/E...lobulin-M/IgM/datasheet.php?products_id=42385
Might be a possible good way for QT procedure, Find out if they have immunity and treat accordingly. In the presence immunoglobulin M (IgM), one may be able to assume there is a built up immunity.
