(apologies in advance for the scientific notation, but I don't know how else to do the math)
In one of Randy's early articles
http://www.advancedaquarist.com/2002/8/chemistry
he dosed 0.1 to 0.3 ml of a ~0.7 Molar solution into a 250 gallon system 2-3 times/week
this is ~2.76e-7 moles iron/gallon
I had 0.1 molar FeCl3 on my bench or 1e-7 moles/uL.
My system is ~140 gallons so I needed 386 uL of the 0.1 molar solution 2-3 times/week
or rounding 1200 uL/week
My topoff tank lasts about a week and a half so I put 2000 uL (2 mL) into the topoff tank every time I fill it up.
Sorry again for all the math, but bottom line is FeCL3 stays in solution and no reason not to put it in the topoff. Then I only have to remember every week or so, not every couple days.