You cannot assume that - if you had shorts in more than one string, then changing configurations (i.e. running all strings in parallel vs. running single strings on single drivers) would certainly change the functional result.
Of course I cannot say you do or do not have shorts, but from what you've posted I can say that multiple shorts COULD act like that. At any rate it's really easy to test for. Set your multimeter to continuity, clamp one probe to the heatsink, and go around to each LED touching the other probe firmly to each pad on each LED. If you ever get a reading or beep anywhere, you have one or more shorts.