I don't know much about this product since it is FDA approved and given by Vets. Sounds interesting.
From the manufacturers website:
What is Comfortis?
Comfortis is the first FDA-approved, chewable beef-flavored tablet that kills fleas and prevents flea infestations on dogs for a full month. Comfortis requires a prescription from your veterinarian.
For:
Dogs (14 weeks of age or older)
Benefits:
"¢ Starts killing fleas within 30 minutes
"¢ Lasts a full month
"¢ Kills fleas before they can lay eggs
"¢ Comes in a convenient chewable, beef-flavored tablet
How it works:
Spinosad kills fleas by causing excitation of the insect's nervous system, leading to paralysis and rapid death.
Cautions:
The following adverse reactions may occur: vomiting; depression/lethargy; anorexia; ataxia (loss of coordination); diarrhea; pruritis (itchiness); trembling; hypersalivation; and seizures. While Comfortis has been found to be safely used with heartworm preventatives that contain ivermectin (e.g., Heartgard Plus, Iverhart Plus) when those products are used according to label directions, the following may occur if your veterinarian prescribes extra label use of a heartworm preventative (e.g., to treat non-responsive demodectic mange and other conditions): trembling/twitching, salivation/drooling, seizures, ataxia, mydriasis (dilation of pupils), blindness, and disorientation. If your pet is experiencing any of the above symptoms, or you notice other differences in behavior (e.g., cough, decrease/increase in appetite), contact your veterinarian.
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More Information:
Brand Name
Comfortis (Lilly)
Generic Name
Spinosad
What is the most important information I should know about Comfortis: Comfortis is a prescription medication FDA approved for use in dogs and puppies 14 weeks of age or older to kill fleas and prevent flea infestations for one month. Comfortis is available in a Pink box for dogs 5 to 10 lbs (140mg), Orange box for dogs 10.1 to 20 lbs (270mg), Green box for dogs 20.1 to 40 lbs (560mg), Blue box for dogs 40.1 to 60 lbs (810mg), and Brown box for dogs 60.1 to 120 lbs (1620mg).
What is Comfortis: Comfortis is a chewable, synthetic beef flavored tablet (derived from pork protein and hydrolyzed soy) that is given to the dog to kill fleas and prevent flea infestations for one month. Comfortis chewable tablets are for monthly use in dogs and puppies 14 weeks of age and older.
What should I discuss with my veterinarian before giving Comfortis to my pet: Tell your veterinarian if you are planning on breeding your pet. Tell your veterinarian if your dog has a history of seizures (epilepsy).
How should this medication be given: Give Comfortis chewable tablets with food. Give Comfortis chewable tablets once a month. Comfortis chewable tablets may be chewed, offered in food, or administered like other tablet medications. If vomiting occurs within 1 hour of administration, redose the pet with another full dose. Store Comfortis at room temperature (68-77° F)
What happens if I miss a dose: Give the missed dose with food as soon as you remember and resume a monthly dosing schedule.
What happens if I overdose the pet: Overdose of this medication is unlikely. However, if an overdose is suspected, contact your veterinarian or veterinary emergency room. Symptoms of overdose that may occur include vomiting.
What should I avoid while giving Comfortis: Your pet may maintain normal activities and interactions while being given Comfortis. The safe use of Comfortis chewable tablets in male dogs intended for breeding has not been established.
What are the possible side effects of Comfortis: Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Comfortis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, redness of the skin, hyperactivity and excessive salivation. Talk to your veterinarian about any side effect that seems unusual or especially bothersome to the pet.
What other drugs will affect Comfortis: Talk to your veterinarian before giving any prescription or over the counter medications.
Where can I get more information: Your pharmacist has additional information about Comfortis written for health professionals that you may read.
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Spinosad
From Wikipedia, the free encyclopedia
Spinosyn D
Spinosad (spinosyn A and spinosyn D) are a new chemical class of insecticides that are registered by the United States Environmental Protection Agency (EPA) to control a variety of insects. The active ingredient is derived from a naturally occurring soil dwelling bacterium called Saccharopolyspora spinosa, a rare actinomycete reportedly collected from soil in an abandoned rum distillery on a Caribbean Island in 1982 by a scientist on vacation.[1] It has not been found in nature since that time, and was subsequently described as a new species. The bacteria produce compounds (metabolites) while in a fermentation broth. The first fermentation-derived compound was formulated in 1988. Spinosad has since been formulated into insecticides that combine the efficacy of a synthetic insecticide with the benefits of a biological pest control organism.
Spinosad topical suspension, 0.9%, was approved by the U.S. Food and Drug Administration (FDA) on 2011-01-18 for the topical treatment of head lice infestation in patients four (4) years of age and older.[2] It is marketed as the trade name Natroba in the US by ParaPRO Pharmaceuticals.[2] Spinosad is a mixture of spinosyn A and spinosyn D in a ratio of approximately 5 to 1 (spinosyn A to spinosyn D).[3]
