I haven't tried general cure on wrasses but will keep that in mind . As for paraguard, I now have that in my protocol . I actually like it and think it very effective. I add that in the bag before I net them into the tank . Of course it's in a bag from the LFS only. If I ever order online, the fish have to be removed from the shipping bag right away. I can't remember the thread but recommendation was to remove the fish otherwise a sharp increase in pH from fish in shipping bags from online retailers. As for general cure , I haven't had any problems . I have used other forms of praziquantel and metronidazole . Still no issues. I like that GC comes in a powder and maybe more resistant to degradation overtime in a sealed packet . As for the other forms like prazipro , it's in a liquid and I don't know how effective it is over a long storage time when already mixed . As for air stone , I always use in Qt/HT . That is my main source of aeration and cheap too since i don't have to have a water mover in there . I usually have multiple tanks going on.