Documented where? Hyposalinity is likely gentler than copper but is still stressful on fish, at least at levels needed to break the cycle w/ crypto.
it's all over this thread, with links provided but here is more.
There may be some concern that hyposaline conditions could be stressful to marine teleost fish, or otherwise potentially harmful. While this is true in extreme salinities, studies indicate that this is not the case in more moderate salinities that would be employed in hyposalinity therapy (Wu & Woo, 1983. Woo & Chung, 1995. McDonald & Grosell, 2006).
The effects of stress caused by capture, transport and handling is a major concern when acclimating fish, especially when they have been bagged for a prolonged period. Stress affects fish in two ways: it produces effects that disrupt or threaten homoestatic equilibrium and it induces adaptive behavioral and physiological responses (Wendelaar Bonga,1997). Osmoregulatory dysfunction is closely associated with stress in fish. This is recognized by an increase in osmolarity in saltwater species (Carmicheal et. al, 1984. Robertson et. al, 1988.). This can manifest in the loss of up to ten percent of body weight due to dehydration in one or two days (Sleet & Weber, 1982.). Reducing the salinity gradient between the water and the internal fluids of fish is effective in counteracting osmoregulatory dysfunction and other physiological responses to stress (Johnson & Metcalf, 1982. McDonald & Milligan, 1997.) With marine teleost species, this is accomplished by reducing the salinity of their environment.
Quickly acclimating recently transported, or otherwise stressed marine teleost fish to low salinity water will help them to recover normal homeostasis more rapidly. Marine fish are most sensitive to changes in temperature and pH during the acclimation period. Match these parameters in the quarantine tank closely to the shipment water, provided they are not at levels that are dangerous to the fish. Then the pH and temperature can be adjusted slowly over a couple of days to match the display aquarium.
Treating Cryptocaryon irritans
Hyposalinity has several advantages over the use of copper or harsh chemical for treating Cryptocaryonosis in fish. Hyposalinity is a safe and effective alternative that is non-toxic and does not cause stress to the fish when used correctly. Copper suppresses immune function and it is toxic to fish.
http://www.advancedaquarist.com/2007/6/fish