yes they can be, but IMO, I think in your case with the Melanarus being that size, he will hold his own and introducing them at the same time or the Melanarus first. Now any wrasse added after the Mystery, anything can happen.
I have both in a 300 gallon. I have a melanarus at least 5" in tank 4 years with a small tusk about 2" for a year then added a mystery about 2". The mystery was lightly pick on for a good week by the tusk and now they are all friends. It's been about 6 months
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