I run them the same way I used to do with KZ stones but I used only 2l of them instead of 3l of KZ stones just to be sure not to overdose. The flow is around 700-800l/hour inside my KZ reactor - I also shake them twice a day just the way I did with KZ. Np pro according to the vendor is a "fuel" to help grow the denitrification bacteria AFAIK in the simmilar way as Zeostart3 is used in Zeovit method but AF products dont have any smell at all (KZ smells kind like a vinegar?). This is what producer claim - as I said it's only 2 days so I don't have any opinion on my own about this specific product yet.
edit - I dose 12 drops of Np pro every day - just a little less than the producer suggests for my tank volume