My journey using Chloroquine Phosphate begins...

[alprazo]

I just never see brookynella anymore. My days of keeping fish with bones are really in the past. I've never tried it.

I can tell you that I successfully treated a group of chromis with Uronema. This is not an obligate parasite and therefore nearly impossible to eradicate from the tank. Even though the chromis improved in QT, when placed into a DT, where it was probably present, it returned and they one by one died.

With brookynella I would still recommend formalin or flagyl.

Brookynella and Uromena are difficult to distinguish and therefore I would stick with the latter two.

 

[b0bab0ey]

Day 46 update: PB Tang continues to show no symptoms of Ich/Flukes. Clown looks good too. Only thing with the Tang is her Lympho has come back a little bit. I can't remember seeing Lympho on her since when I first got her (well over a year ago), although my wife claims she saw it once while the Tang was in the DT. I'm not really all that concerned with it.

I can tell the Tang is tired of being confined to a barren 29g QT. She sleeps in her PVC cave, but whenever the lights are on she usually swims back and forth by the front glass. She goes crazy whenever she sees me (begging for food) so I've been feeding her 3x daily to keep her happy. She also gets nori daily. I can't even get the nori on the fish clip before she starts eating it out of my hand.

She hasn't seen a DT since Jan 1st and if I weren't moving soon, I would have put her back already. I'm upgrading to a 150g as part of the move, so I'm hoping she'll be happy in there. I just hope I don't lose her during the move.

 

[alprazo]

Thx for posting your experience with CP. I hope more people try it and post their results. I have had nothing but success in both ich and velvet. IMO, it is the best treatment out there for these two parasites.

 

[mowhawk]

I too have used CP to treat fish. CP is available in the UK over the counter (from a pharamcy) for malaria prophylaxis.

My experience with this drug is also positive. I have treated a powder blue tang and several other fish that had WS successfully.

The following is an account of my observations:

1) Minimum treatment should be over a period of 14 days.

2) Dosage should be 5-10mg/l

3) I carried out partial water changes every three days and ensured I replace any CP that was removed by the water change and any that was broken down by the effect of light.

4) I ran a skimmer during treatment (not usually recommended) however I turned the flow through the skimmer down to prevent the skimmer from removing the CP.

5) CP kills algae, inverts and corals (except hermit crabs).

6) The fish responded quicker to CP than copper medication; WS cleared up within 3 days.

7) Treating in a QT is far better and effective than feeding CP directly to fish.

I never observed any ill effects (like cloudy water) during treatment time, however I lost a flame angel early in treatment (prob due to CP overdose).

HTH

Sanj :wave:

 

[VeL]

Great thread and big thanks to everybody who is sharing their experience with CP. I myself am fighting Ich outbreak (I think) that I could not eradicate during the 4 weeks copper treatment. During all times copper levels were 0.5-0.6 (tested with 3 test kits) but the parasite still remains. I have doubts that it may not be Ich, as the parasite looks bigger/longer-worm-like but not copper nor PraziPro (double treatment) killed it and it keeps appearing on fish.
So now I managed to get some CP drugs (pills with active ingreadient 250mg CP) and I am about to treat my 100l QT. My initial plan was to use 10mg/l as suggested here, however I stumbled upon this thread:

http://www.reefcentral.com/forums/showthread.php?t=2027415

Under post #6 you can see scanned pages from FAMA magazine, where Bob Goemans suggest using:
1) for QT purposes - 10mg/l CP and then repeat the dosage in 10 days
2) for disease outbreak - 20mg/l CP and then add aditional 10mg/l CP every 7 days till you hit 40 days treatement.

So I was wondering if 10mg/l with no second dose would be sufficient to eradicate the parasite. My fish have gone through so many medicines and I am not sure if they would handle more if I had to make a second CP treatement if the first one does not work.

 

[mowhawk]

Great thread and big thanks to everybody who is sharing their experience with CP. I myself am fighting Ich outbreak (I think) that I could not eradicate during the 4 weeks copper treatment. During all times copper levels were 0.5-0.6 (tested with 3 test kits) but the parasite still remains. I have doubts that it may not be Ich, as the parasite looks bigger/longer-worm-like but not copper nor PraziPro (double treatment) killed it and it keeps appearing on fish.
So now I managed to get some CP drugs (pills with active ingreadient 250mg CP) and I am about to treat my 100l QT. My initial plan was to use 10mg/l as suggested here, however I stumbled upon this thread:

http://www.reefcentral.com/forums/showthread.php?t=2027415

Under post #6 you can see scanned pages from FAMA magazine, where Bob Goemans suggest using:
1) for QT purposes - 10mg/l CP and then repeat the dosage in 10 days
2) for disease outbreak - 20mg/l CP and then add aditional 10mg/l CP every 7 days till you hit 40 days treatement.

So I was wondering if 10mg/l with no second dose would be sufficient to eradicate the parasite. My fish have gone through so many medicines and I am not sure if they would handle more if I had to make a second CP treatement if the first one does not work.

I have found 10mg/l to be sufficient to treat WS.

However I do partial water changes and add extra CP at the same time (replace CP for a like for like basis).

HTH

Sanj

 

[b0bab0ey]

Just wanted to thank the above posters for contributing to this thread. As others have already noted, CP was considered a "proven treatment" for Ich and Velvet back in the 70s and 80s. Apparently it fell out of favor simply because it became so hard to get. However, alprazo has a veterinary pharmacy contact who can sell you the medication. Look here for more info:

http://www.reefcentral.com/forums/showthread.php?t=2152307

Look folks, I'm not saying this stuff is a "miracle cure", as I myself have limited experience with it. All I'm saying is unless people start using it and posting their results, newbies are never going to move past treatments like hypo (which is tedious and doesn't work on all strains) and copper (which is a poison - need I say more). Also, for what it's worth, I think tank transfer sounds like a helluva good option as well. Just be prepared to spend a lot of $$$ on salt. So, I guess it's whichever option you wanna spend your $$$ on... CP or salt.

 

[alprazo]

Mohawk,

I WOULD NOT dose 20mg/l and add every 7 days. Stick with 10mg/l or 40 mg/gal.

 

[mowhawk]

Mohawk,

I WOULD NOT dose 20mg/l and add every 7 days. Stick with 10mg/l or 40 mg/gal.

Neither would I :hmm5: 20mg/l was Bob Goemans suggestion and NOT mine

 

[VeL]

b0bab0ey sorry to invade your thread but I think it will be good to keep all feedback on CP in one thread so people can read it all.
Anyhow. After treating ich (I think, or some type of crypto) with copper at 0.5-0.6 for 4 weeks and after the syptoms kept showing over and over again I decided to give it a try on CP. On 3rd of May I bought some anti-malaria pills that have 250mg CP active ingreadient per pill. They have cornstarch and some other minor ingreadients which make the water cloudy but I can't find pure CP here. After making 4 pills /1000mg CP/ into powder, I disolved them in a plastic cup and shortly after added them to my 100l QT, which gave me concentration of 10mg/l. The QT lightning is turned off. Three days later once again I saw white spots on the Regal Tang and I decided to increase the dose with 25%. After some water change with the appropriate dose of QT added to the new water, i put 250mg more, which gave me 12.5mg/l. I also added the recommended dose of PraziPro /I may have flukes too/. Five days passed but the Yellow Tang still breathe a bit fast. Today I also saw a possible white spot on one of the clowns, which may also be a little wound - it is very tiny and I cannot see good but seems to be ich. However what worries me more is that the yellow tang has been scratching on the pvc pipe all day long.
Today I will do a 40% WC, redose Prazi at full dose and redose CP for the new water.
As alprazo mentioned the symptoms should disappear in a few days, however I still see them 7 days later. So I am wondering if I should wait or increase the dose to 15-20mg/l in case I have some very resistant Ich strain, which survived copper and keeps thriving in CP.

 

[alprazo]

The malaria pills are perfectly fine.

I would not go past 12.5 mg/l. I have to look back, but in my initial research, I remember the LD50 being somewhere around 20 mg/l.

If your disease has failed copper and not responding to chloroquine, it is unlikely that you are dealing with crypto. I'm sure resistance to chloroquine exists in nature, but copper too- I would think is less likely.

 

[b0bab0ey]

b0bab0ey sorry to invade your thread but I think it will be good to keep all feedback on CP in one thread so people can read it all.

You're not invading; You're adding useful information to this thread, my friend. The more folks we can get to experiment with CP and post their results, the more we grow in knowledge as a fish disease fighting community.

I would give CP the same treatment time as copper (3-4 weeks) before giving up on it. It took my PB Tang (Typhoid Mary) that long to stop showing all symptoms. Speaking of which, Mary is still doing great! Hopefully she can make the 12 hr move this weekend to her new home, a 150g reef.

 

[VeL]

You're not invading; You're adding useful information to this thread, my friend. The more folks we can get to experiment with CP and post their results, the more we grow in knowledge as a fish disease fighting community.

I would give CP the same treatment time as copper (3-4 weeks) before giving up on it. It took my PB Tang (Typhoid Mary) that long to stop showing all symptoms. Speaking of which, Mary is still doing great! Hopefully she can make the 12 hr move this weekend to her new home, a 150g reef.

I really hope that 3-4 weeks treatement is what I need and that the CP treatment is working for me. It has been 12 days now in CP and the respiration problems have been present at all time. At the begining I thought there were flukes as well so I've done two 5 days PraziPro treatments together with the CP without any improvement. For the past two days the respiration rate of the clowns has icreased a lot and the tang and clowns have been scratching badly but what's worse - I saw two very small white spots and a bigger white spot on one of the clowns. I can't believe it's been 3 days at 10ppm and 9 days at 12.5 ppm of CP and symptoms seem to develop :sad2:

P.S.
On Wednesday I'll perform 80% WC and to the new water ill add a fresh dose of 12.5 mg/l CP /malaria pills again/. The only thing I could think of is that the 20 mins a day when the lightning is on may break down CP to a point where it is not effective anymore. Or it may be PraziPro that makes CP less effective. But again that's only an assumption.

 

[Chicago]

Tagging

 

[Chicago]

Need source got quilarium. Sorryon spelling

 

[b0bab0ey]

Day 84 update: PB Tang has been living in a clear 27 gal sterilite container for over 2 weeks now. I've got an AC 50 HOB running on it (w/a seeded sponge) and that has been keeping the ammonia at 0. I've had all sorts of problems with my new 150 gal tank (mostly plumbing) but it's up & running now, and I've begun moving my livestock over, so hopefully she will see the tank sometime this week. She hasn't seen a DT since 1 Jan. She still looks great, eating great, etc. I will take some pics of her and post them once she's in the new DT.

 

[b0bab0ey]

She made it!

She made it!

Day 97 update: Almost 100 days later, my PB Tang is finally in her new home - a 150 gal mixed reef. She's survived Ich, a 12 hr move, and living in a 30 gal tank (then sterilite container) for all of that time. See pics below!

 

[blennielove]

Congratulations!!!
:bounce2::bounce1::bounce2::bounce1::bounce2::bounce1::bounce2::bounce1:
I know how difficult it is sometimes in our hobby to make the right decision. Best wishes to your PBT in her new home!

 

[b0bab0ey]

Just wanted to give a quick update: Since my last post, I have successfully QT'd 3 rounds of fish by treating prophylactically with CP and then PraziPro. All fish were treated in the same bare bottom style QT as described in post #5. No losses, everyone did fine with no noticeable side effects. The only symptom I ever noticed on any of the fish was some Lympho on a CB Angel.

For the record, here are the fish I QT'd: CB Angel, Flame Angel, Kole Tang, CB Butterfly, Royal Gramma, 2 Maroon Clowns, Moorish Idol, Achilles Tang. I'm very pleased with the successful treatment of the last two. Some of these fish I sold/traded, some I kept and placed in my 150 gal DT. If I ever notice any disease symptoms from the fish I kept, I will update this thread with that info.

 

[vaporize]

I was reading somewhere that public aquarium now mix it into the fish's food to enable it to enter the blood stream, suppose to last 30 days and can be used in a reef setting (if the food is injested by the diseased fish).

Try anything like this?