Prazipro vs API General Cure

skene

New member
I've been reading that the contents of General Cure is more effective with flukes & internal worms than Prazipro but most people seem to be using Prazipro instead when QTing new arrivals prophylactically.

Any reason(s) why?
 
A few reasons why I treat with Prazipro prophylactically, but am more reserved when it comes to using medications containing metronidazole (like General Cure):

1. Prazipro contains a stronger concentration of praziquantel (9.46 mg/gal) than General Cure (7.5 mg/gal). While both should get the job done, I like praziquantel a little stronger for eradicating gill flukes being it's such a mild active ingredient.

2. The other active ingredient found in General Cure is metronidazole, which is mostly used to fight intestinal worms/parasites. Metro is not as gentle on fish as prazi IME, so I don't like to expose fish to that unless I have to.

3. Gill flukes (treat with Prazipro) can have subtle, almost unnoticeable symptoms. There's nothing subtle about a fish swimming around with a 6 inch long stingy white poop hanging out of his butt. :lmao: And that's when you know you have a fish afflicted with intestinal parasites and it's time to use metro. ;)
 
A few reasons why I treat with Prazipro prophylactically, but am more reserved when it comes to using medications containing metronidazole (like General Cure):

1. Prazipro contains a stronger concentration of praziquantel (9.46 mg/gal) than General Cure (7.5 mg/gal). While both should get the job done, I like praziquantel a little stronger for eradicating gill flukes being it's such a mild active ingredient.

2. The other active ingredient found in General Cure is metronidazole, which is mostly used to fight intestinal worms/parasites. Metro is not as gentle on fish as prazi IME, so I don't like to expose fish to that unless I have to.

3. Gill flukes (treat with Prazipro) can have subtle, almost unnoticeable symptoms. There's nothing subtle about a fish swimming around with a 6 inch long stingy white poop hanging out of his butt. :lmao: And that's when you know you have a fish afflicted with intestinal parasites and it's time to use metro. ;)

I agree. While I do not believe in using drugs prophylactically in most cases, I do advocate Prazipro for all incoming fish.
 
Just to update this thread with my personal experience:

I've been having great success using API General Cure after two treatments of PraziPro. Wrasses that were acting lethargic, wouldn't eat, hid all the time even after PraziPro treatments, all perked up and ate like champs after final rounds of AGC.

I did, however, cut down on the suggested dosage of AGC (in a 150G QT, dosed 100G AGC) to be on the safe side, after reading reports of certain species being sensitive to this particular medication.

Has anyone else had success treating with AGC even when using less than suggested amount?
 
Bump :)

Has anyone else had success using less than the recommended dosage of AGC to treat flukes / internal worms? (About 2/3 the recommended dosage in my case)
 
Not I, but I do have success using fw dips for external flukes and Levamisole (sold as pigeon dewormer) for (stringy poop) internal worms - I've found it to be gentle, yet effective and tend to skip metro as an option. One clown died the day after I dosed Levamisole, but it was probably not a direct consequence of the Levamisole itself, he stopped eating for over a week and had finished marine velvet treatment the day prior.
 
A few reasons why I treat with Prazipro prophylactically, but am more reserved when it comes to using medications containing metronidazole (like General Cure):

1. Prazipro contains a stronger concentration of praziquantel (9.46 mg/gal) than General Cure (7.5 mg/gal). While both should get the job done, I like praziquantel a little stronger for eradicating gill flukes being it's such a mild active ingredient.

2. The other active ingredient found in General Cure is metronidazole, which is mostly used to fight intestinal worms/parasites. Metro is not as gentle on fish as prazi IME, so I don't like to expose fish to that unless I have to.

3. Gill flukes (treat with Prazipro) can have subtle, almost unnoticeable symptoms. There's nothing subtle about a fish swimming around with a 6 inch long stingy white poop hanging out of his butt. :lmao: And that's when you know you have a fish afflicted with intestinal parasites and it's time to use metro. ;)

Do you use metronidazole in food or in water?

What dose do you use?
 
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