I am dosing 2 vials of BioDigest every two weeks in my 220gallon.(I have a total of 300+gallons in my system) I have not had any ill effects,RTN, or any other problems. I think it is best to follow the manufacture's recommendations on dosage. I have seen nice polyp extention and colors seem to have deepened a bit. According to the directions Dose 1 vial of BioDigest for up to 1000 ltrs.(approx.250gals) I have a little over 300 gallons in my total system hense 2 vials. I have been dosing for almost 4 months now with no problems. As for the Reefbooster I dose 3 vials every week on sunday evening.s I dose all other products every 14 days sat. evenings. I do my water changes on Fridays once a month the day before I dose the BioDigest, BIOPTIM ,Stronti+, and Iodi+ . I also run a Carbon reactor along with a Phosphate reactor, 24/7 change them out every 14 days on fridays.
I dose every 14 days :
2 BioDigest
6 BIOPTIM
1 Stronti+
1 Iodi+
I also dose every 7 days one day later in the week :
3 Reefboost
I do a 30% water change once a month the day before I dnse the majority of the Prodibio . My water parameter are as follows:
salinity 35 PPt
Ph 8.3
Temp 77F
Calcium 450ppm
Alk. 12.5 dKH
Phosphate 0
Nitrate less than 3 ppm
Mag. 1350 ppm