Sure. I use a Read Sea Ozonizer, which is outfitted with a controller ( the controller will allow you to set your target ORP and shut the ozonizer off when it reaches that mark). Make sure that you buy a unit with a controller. If not, make sure that you have an aquarium controller that can monitor ORP and act as a controller and shut your ozonizer down once ORP reaches the targeted value. I also purchased an air pump, air dryer and some 1/4" ozone proof tubing.. I connect the the air pump to the air drier. Then out from the other side of the air dryer to the inlet on the Ozonizer. Then, using ozone safe tubing , I connect the outlet of the ozonizer to the air inlet on my skimmer using a lee's T from Petland stuffed into a 1/2 inch (length) piece of 1/4" ozone proof tubing. I stuff that into a 1/4" john guest fitting and that connects to the air inlet on the skimmer..
The john guest valve is used to control the air input in to my Deltec Skimmer. The Tee is used simply because you don't know for sure if the air pump is delivering enough air to the skimmer in order for it to operate properly. After all, it has to push air through the dryer and ozonizer... who knows without an air meter how much air is actually getting to the skimmer at this point? So, the open end on the tee ensures that the skimmer is getting enough air along with creating a vacuum for the the ozone as well.
Dry air is very important for Ozone efficiency. If the air in the room is damp, it is beneficial to use an air dryer. The air dryer is stuffed with silica beads, which can be emptied into an oven-safe pan and literally baked in order to re-charge them (Dry them out). They turn pink when the are saturated and turn Blue/Purple when the are dry. If the air is very dry in the room, then an air dryer may be unnecessary. I don't use one in the summer because the window in my tank room is left open. However, as the winter approaches, I have to close the window and use the air dryer because the dampness increases.
I know this looks like a lot, but it's actually very simple. Depending on your skimmer, you may have to jerry-rig your connection a little different.
Once all connected, set you ozonizer at a mg/hr rate that is acceptable for your skimmer, set the target ORP and sit back and watch how clear your water will get.