I treated as directed when this first came out. all the bryopsis died out and was gone for 3 months or so. Then it came back and I retreated at a slightly higher dose and it disappeared quickly. Today I noticed it coming back. My last dose was several months ago. Kind of concerning.
Is it possible to keep a low maintenance dose going for multiple months? Maybe an extended period of time of low saturation will fully kill it off.
Maybe do a regular dose, let it sit like instructed.
Dose your new saltwater BEFORE your water change with a 75% strength dose. Do your water change, then let it sit.
Next water change rolls around, do the same thing but a 50% strength dose to the fresh saltwater BEFORE your water change. Do your water change, then let it sit.
Same thing as before, but this time 25% strength. Complete same process as before.
From there on out do normal water changes without any medication being dosed, let it slowly dilute itself from your system. Even at that rate it will be in your system for awhile.
In my honest opinion if I was in your shoes, I would try what I recommended above. I see no I'll effects happening other than losing any purposely kept refugia algae, ATS, etc.
It's your call, and maybe worth a shot...keep us posted no matter what outcome or solution you chose.