Granulated activated carbon(gac)removes some but not all organic materials and whatever is bound in them including ; metals, nitrogen, phosphorous, allelopathic compounds. I would not run a reef without out it ,personally. The recommended dose is 1/2 cup, ie 8ozs per 50 gallons of system water volume changed monthly.If rox8 gac is used only 1/3 cup per 50 gallons of system volume is recommended. Gac will not remove inorganic nitrogen(NO3) ,phosphate (PO4), and other things such a metals which may occur when the organics breakdown in the tank.
Granulated Ferric Oxide(gfo) , adsorbs inorganic phosphate(PO4), some silicate and a few other things of no cosnequence. It may add some soluble iron to the tank which is benign to beneficial in small amounts. It should be rinsed to prevent dust from entering the water. Some forms (granular vs pellet vs HC) require more rinsing than others.
Either gac or gfo can be used in a canister filter or just a fine mesh bag in the sump. The most effective application is in a reactor( a container where water is pushed through the media via a pump/powerhead ). I use the BRS dual reactor and and a couple of Two lLittle fiFshes reactors on my system. I prefer the Two Little Fishes reactor . In my experience : it's easier to change out , accomodates a bit more flow through it .It's clear plastic allows a good view of the media and water flow where the media is not observable to detect clogs. precipitation, bacterial buildup ,etc. in the BRS reactor.