I just popped my rock into the tank right out of the box and let her rip. I did inspect for hitch-hikers but I did not get them all. Luckily, there were no AEFW, red bugs, etc.
The macro went wild to the point of being a problem, but the inhabitants took care of it later on. I let my system run for months, first just with mechanical filtration, then I added 11 chromis, then a skimmer, etc. but I did not put in the rest of the fish or any corals for quite some time.
What I did get was some sweet coraline algae (although it is some sort of super-growing version) various snaila including some cool stomatella, plenty of pods, mysid, etc. and various corals.
I am not sure I would do it that way again, but as far as my rock goes, I have been really happy with it. My theory at the time was, why pay for live rock, and then kill everything off it?
First day: