IMO, good sourced and filtered seawater has a much lower risk than error prone human made salt mix that can't replicate natural sea water. Not to mention almost every salt mix available is not even close to average NSW parameters nor does it actually contain all of the elements and minerals found in the sea. I suspect this is why so many wild and/or maricultured corals don't survive once introduced to hobbyists tanks. Or at a minimum, take an extremely long time to adapt to the change.
I've read 100's of threads about deadly necrosis event parameter swings from doing something so simple like a water change. How much of the unexplained coral loses account for artificial salt mix? Happened to me with a bad batch of RSCP. A lot of people have opinions on using NSW, yet they've never used it and I have yet to find the thread or report that says NSW is bad for our animals that came from.... the sea. In fact, every report is just the opposite. Inhabitants immediately react positively. More vibrant color and better polyp extension. This has been my experience too. Paul B is a good example and he collects from dirty NY. Many people in Florida do it as well. Hell, California has a company that actually sells filtered NSW. Many coastal public aquariums use filtered sea water. Many collectors pump seawater right into their holding systems.
Ultimately and again, IMO, artificial salt mix likely has at least an equal risk compared to NSW, probably a lot more. But, you need to know how, where and when to collect and also how to filter the water.
Here's a good read on the toxicity of artificial salt mix.
http://www.reefkeeping.com/issues/2003-03/rs/feature/