Nothing wrong with reviving an old thread if more information is needed.
The best way I found (after obvious trial and error ...) was to first wear rubber gloves. Because these nasty buggers squirt, I would also suggest eye wear for protection.
Mine used to grow out of control and I used to just pinch them off in the tank. However, along with almost killing me, the toxin affects the other corals too, so this isn't a good idea.
Instead, I would plan to remove them AFTER I did a water change. I would have two separate buckets of old salt water. After prying off however many polyps I wanted gone, I would rinse in one bucket, then the other. Usually this kept the toxins from getting back into the tank and causing problems.
After you are done, please make sure all utensils are washed in hot soapy water, and as a precaution, I'd soak them in vinegar and/or bleach afterwards. I would suggest using paper towels so you can throw them away when done. Be sure not to wipe your face with the used paper towels. Wash your hands in hot soapy water, and maybe rinse in vinegar.
Palythoa toxins are not something to mess with. It didn't bother me for years and then suddenly ... boom ... toxicity build up is bad kids, mkay?
Be careful.
Nasty little polypses .... :twitch: