The box would be starved for water and produce a great deal of bubbles, it may be possible if you packed it loosely and submerged it completely, but at the normal installation depth the pump out rate would exceed the intake capacity and as the media clogs, cavitation will be an issue. For comparison the 6208 Wavebox is basically the same box with a 6095 and the pump can empty the filter box in a bit over a second at the normal operation depth.