The frog spawn can sting the zoos if it touches them as I figure you probaly know seeing how you ask how much space. I would just keep them far enough a part so that when either spreads or grows they still will not touch. Good luck
I had a problem with my frogspawn and zoos because my zoos were down "stream" and the stinging tentacles of the froggy were slowly killing them. They were a good 8 to 10 inches apart too.
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