I think the alkalinity is almost immaterial (within normal ranges of about 7-11 dKH) as long as it is not an SPS tank, or as long as it doesn't become ULNS, even if it is an SPS tank.
I've dosed vodka, vinegar, and vinegar saturated with calcium hydroxide manually once or twice a day, but I presently dose normal vinegar using a BRS 1.1 mL per min dosing pump, spreading the dose out over the daytime hours.
I think a higher starting dose with vinegar is OK because lots of different creatures use acetate and I don't think it will accumulate, even in the absence of bacterial populations to consume it.