Well, r0bin, welcome to the world of reefing, where there are loads of options.
The Brita filter would save you the trouble of using a dechlorinator, and that's about it. I'm not sure that it'd be useful for 300 gallons, and it doesn't seem to remove much.
You can get a pure DI unit (Kati and Ani are two such products), buy bulk resin, and that'll work. It will be cheaper up front than RO-DI, and might be okay long-term. The prepackaged products are going to be very expensive long-term, I think.
Plain RO might be fine. A lot depends on what is in your tapwater. You could try it. RO-DI is the best you can do. A unit will run $100-200, depending on quality.