Cupramine only works on Cryptocaryon and marginally against velvet. Prazipro is only effective against flukes, and Paraguard has no empirical studies that demonstrate its effectiveness.
Copper which obviously is in Cupramine is the primary treatment for ich and velvet in the reefing community. Whether or not it works marginally on velvet is a matter of opinion. However there is more evidence on it working than any other product on the market, including CP. (that may change soon with CP's resurgence, who knows!). It is my preventative
medication of choice for both (obviously there are non medication based treatments like hypo and TTM) and is sufficient IMO along with the majority of the reefing community (based on my experience and research). Having said that, I have always hated the idea of using copper, it makes me feel like im running chemotherapy. I would use TTM for ich but due to my work travel schedule it is just not possible.
Prazipro is effective against more than just flukes, also flat worms, tape worms, and turbellarians.I have no idea if it has any effect on uronema however. I doubt it because i have never heard of that, although it is a parasite....
I have had success using Paraguard to prevent/treat brook. I also know many other people who do the same. That is all i use it for. It is basically designer formalin. It does not have "empirical evidence" that i know of, but scientifically it makes sense and certainly has sufficient anecdotal evidence based on my research. The main reason I use it for brook is because I know a clown breeder who recommended it to me over formalin and he has 40 years of experience. I trust his opinion.
So for me the only question is, do any of these medications (prazipro?) prevent/treat uronema or is CP the only one with any evidence of success (empirical or anecdotal?) That is the only major ailment i dont have covered. Besides bacterial/fungal infections which i have other stuff for.
CP sounds great but I am just not convinced its a better option than the 3 medications above for everything but uronema.
Does anyone have a link to the study on curing dead chromis with uronema? haha thats kind of suspicious to me, why wouldnt they do it on live chromis with uronema. It almost subtly appears to prove it doesnt work fast enough:crazy1: