Considering artificial seawater mixes are man's best attempt at recreating natural seawater, if you have a good clean natural seawater source your good to go with it. For collecting directly off the beach, only on an incoming tide during good weather.
(and there lies the rub
)
i would also recommend giving nsw a 'full sterilization' protocol w/ bleach, and/or uv, before using it in a 'home' system. it's easy, safe, and prevents ALOT of pathogens (presumably) found in nsw from getting into the system.
i worked for awhile for a (now defunct) small importer/whoresaler near oxnard ca, and they used water pumped in directly from port hueneme. the water was treated w/chlorine bleach for a day or so, then the bleach was removed, iirc, by using sodium thio and carbon. worked very well, never an issue
having said that, ...
given the present configuration of some of the salts available today, i can't see any major benefit in using nsw over artificial salt mixes. if anything, the avoidance all of the pathogens and organics of nsw, along w/the risk of introducing pollutants (known and unknown), makes using an artificial mix a 'no brainer', for most.
(and given the success w/ so many species being captive bred using salt mixes, that whole 'toxicity of salt mixes' thing/'theory' of which shimek was such a shill for has pretty much been proven to be absolute 'bunk', for all intensive purposes).
sadly, today there are alot more unknowns for the hobbyist re: what's in nsw, compared to what hobbyists know about what's in artificial sw.
when you use nsw, you're also introducing (for example) 'micro plastics' into your system. that can't be good, for anything. (just one of many examples of the 'modern ocean's' ingredients list)