*******Disclaimer*******
If you use this medication it is at your own risk. No one but yourself is responsible for your actions with this medication. Please read carefully and follow the directions. This medication will most likely kill off all crustaceans in your aquarium.
This medication was first tested in multiple sterile hospital tanks. The dosage and its effect on corals and other typical aquarium animals was determined at this stage.
The second stage took place in 7 reef aquariums owned and/or operated by 7 different people. It took 2 â€"œ3 months to get to this point.
The third stage is taking place right now. The medication name has been released and the treatment protocol posted. I would assume people will be treating their tanks on their own before the end of February.
As you can see this medication has gone through a rather small amount of testing and not much time has gone by. All of the results have been positive so far. However, only time will tell if the red bugs will return to treated systems. Time will also tell if there is some sort of sort of side effect that will pop up a year or more from now. I need to make this point clear.
If you use this medication it is at your own risk. No one but yourself is responsible for your actions with this medication.
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Ok, here is the moment many of you have been waiting for. We (myself and the volunteers) feel this medication is effective against red bugs, and probably safe enough to use in a home aquarium.
The medication is a DOG heartworm medication called Interceptor, it is only available from a veterinarian with a prescription. The tablets used in the initial treatments were for large dogs, 51-100lbs. These tablets are just under 1 gram each and contain 23mg of Milbemycin Oxime, the rest of it is a lovely smelling beef flavor. This chemical is active against Nematodes (Heartworms in dogs) and select arthropods (some types of Mange in dogs). Luckily, our red bugs are one of those select arthropods. The tablets come 6 to a box.
Here is the official information from Novartis on the medication.
http://www.ah.novartis.com/products/en/cab/interceptor.shtml
Refer to this thread and read the whole thing before you begin the treatment.
http://reefs.org/phpBB2/viewtopic.php?t=43945
The dosage used in an aquarium to kill redbugs is 25mg (0.025 grams) per 10 gallons of actual tank water . That is 25mg of the entire tablet. Each tablet in the pack of 6 will treat about 380 gallons. The tablets are ground with a mortar and pestle into a fine powder.
Do your very best to calculate your actual water volume. Take into consideration your sump, oversized plumbing and things like that. All of the initial tests were done with the estimated volume of live rock and live sand subtracted from the total gallons. You need to make sure that every part of the system that’s capable of holding water is treated. This means your refugium, the water inside your calcium reactor, the water inside your skimmer while it is not foaming.
Measure out the Interceptor on a very accurate scale that is capable of reading down to 0.001 grams. Remember, the dosage is 0.025grams per 10 gallons. For safety’s sake get as close as you possibly can. It has been pointed out that it may not be necessary to get down to the 1/1000th of a gram point when we are guessing on the actual water volume. This is an excellent point, however, since we are pretty much guessing our water volume, we should do our very best to make sure that we treat that guess accurately. We don’t want to over treat an over estimate.
Before adding the medication to your tank, turn off your skimmer (water needs to run through it, but you do not want it producing any bubbles. Remove any mechanical filtration if present. Remove any carbon if present. Turn off UV sterilizers and ozone generators.
Remove any shrimp or crabs that you want to save. They will have to stay out of the system for the duration of the treatment. Remember, that when you add them back to your tank, there is a slight chance that you will re-introduce the red bugs to your tank.
The medication is dissolved into some aquarium water (it is not easily soluble, you will have to stir for a while) and spread evenly across the surface of the water. Your tank should remain perfectly clear and look very normal the entire time. The bugs hang on well into the 4th and 5th hour of the treatment, dont be alarmed. Many of the bugs will hang on for days even after they are dead.
If anything goes wrong during treatment perform a water change ASAP and add a large amount of carbon to your system.
After 6 hours, a 25% MINIMUM water change is performed and as much activated carbon as you can fit should be added to the tank. In the initial tests, crustaceans that were reintroduced to a tank after a 25% water change and carbon were unaffected by the medication.
24 hours later the water should be changed again and the carbon replaced.
There is no maximum for the water changes or carbon, the more you do the better.
The treatment needs to be peformed a MINIMUM of 3 times. We know it kills the bugs, but we don’t know enough about their lifecycle to determine if it kills them at every stage of their life. We have to assume that all of the most of the adults are killed in the first treatment. The goal of the second treatment is to clean up any left over adults, and any juveniles that have hatched out of eggs that might have been unaffected. The third treatment is a “just in case†treatment, its goal is to get any bugs that could have possibly survived the first two. I know that three treatments sounds scary, after the first one you will feel much more comfortable with it though.
The frequency of the treatments has yet to be fully determined. Some of the volunteers in the testing did the first two treatments 7 days apart with the 3rd treatment 14 days after the second. Some did 3 treatments 7 days apart. Personally, I have been doing 2 treatments 24 hours apart every 7 days. I will repeat this 4 times for a total of 8 treatments.
The medication seems to be fairly safe, since we dont know the life cycle of the bug its best to err on the side of caution and treat several times. Pretend its an antibiotic, if your going to use it once, make sure you do the whole treatment process at least 3 times!!!
Refer to this thread and read the whole thing before you begin the treatment.
http://reefs.org/phpBB2/viewtopic.php?t=43945