At the time I only ran the biowheel as that was all that would fit on the back on the 10g (no skimmer at all). If you replace a cup of water each day (everyday), with some good salt mix you should have excellent results as long as your not over feeding and your tank is not cycling or curing live rock. The skimmer is great for creating ultraclear water, however, that biowheel on a 10 gallon would clear your tank just as well (use the carbon inserts). Would strongly reccomend replacing a cup or two of water each day. If you decide to replace the biowheel in the future, buy a used one from the RC selling thread, these are the reasons why I like it better:
* the return is smoother (the biowheel return seems to create sprinkles of water all around my 10g, including the front glass, like a fine spray mist over time, I guess the nature of the biowheel spinning and hitting the water)
* the remora seems to do a better job at keeping the water ultra clean
* no cloging issues with the impeller
* no carbon replacement or cleaning or mechanical failures, pretty much automated
* seems to be able handle what ever you throw at it, vs, I always had the feeling that the biowheel biological aspects were limited in gross volume and the carbon/polyfiber inserts seemed like they were always full of deitris.
Note: I also run a ehiem canister with live rock rubble and carbon in the corner with my remora.
Conclusion: You will be fine with daily waterchanges, but you will probably want to upgrade down the road, the Remora is a good option.